Correlation between immunological variables at baseline and overall survival (OS). The percentage of circulating total lymphocytes (A), CD8+ T cytotoxic cells (B), CD4+ follicular T helper 17 cells (C), CD4+ follicular T helper 1/17 cells (D), CD19+ B cells (E) showed significant positive correlation with OS. The percentage of circulating CD19+ memory B cells (F), CD45+ total monocytes (G), classic monocytes (H), inflammatory monocytes (I), and the serum concentration of APRIL/TNFSF13 (J), and interleukin (IL)-2 (K), showed a significant negative correlation with OS. Correlation studies were performed using the Spearman’s rho rank correlation test.