Table 2.

Role of Akt in meiosis progression.

Meiosis Stage	Akt Role in Meiosis	References
Prophase of 1st meiosis	Akt is involved in CDK1 activation and GVBD induction during meiosis resumption	[42,43,44,45,46]
MI/MII transition	Akt is required for the transition from meiotic metaphase I (MI) to metaphase II (MII)	[39,43,47,48,49]
MI and MII-phase	Akt participates in the formation and stabilization of the MI and MII meiotic spindles	[43,48,50]
MI and MII-phase	Akt contributes to centrosome integrity in oocytes	[43]
Meiosis completion	Akt is necessary for completion of meiosis	[47,48,51]