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. 2023 Jul 21;13(14):2433. doi: 10.3390/diagnostics13142433

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Study flow diagram. (a) Pre-BCID2 implementation period. Bloodstream infection diagnosis was based on the results of conventional microbiological methods. The pre-BCID2 cohort included retrospective data from ICU patients with a confirmed bloodstream infection, collected during the immediate six months preceding the implementation of the BCID2 Panel. (b) BCID2 implementation period. The BCID2 cohort included prospective data of ICU patients with a confirmed bloodstream infection, collected for a period of six months upon implementation of the BCID2 Panel. Pathogen identification was conducted using the BCID2 Panel, in addition to standard conventional methods. Bloodstream infection diagnosis was based on BCID2 results, unless they were discordant with those of the conventional approach, in which case conventional results were considered for diagnosis.