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. 2023 Jul 28;102(30):e34444. doi: 10.1097/MD.0000000000034444

Table 2.

Correlations between the expression changes in pre- and post- neoadjuvant chemotherapy and therapeutic effect.

Protein Imaging efficacy Pathological efficacy
r P value r P value
Expression Change of HDAC1 0.390 <.001 0.138 .215
Expression Change of xCT 0.063 .576 0.029 .798
Expression Change of GPX4 < 0.001 1.000 −0.034 .763
Expression Change of ABCB1 0.090 .424 0.006 .959

Correlations between the expression changes of RAC1, HDAC1, xCT, GPX4 and ABCB1 in the pre- and post- NAC and therapeutic effect.

ABCB1 = ATP binding cassette subfamily B member 1, GPX4 = glutathione peroxidase 4, HDAC1 = histone deacetylases 1, xCT = glutamate-cysteine reverse transporter protein.