Table 1.
Cardiac parameters measured by 2D ultrasound in WT and MFS treated (+) or not (-) with potassium oxonate (PO; in weeks). (------ means starting point where PO was not administered yet).
| WT | WT | WT | WT | MFS | MFS | MFS | MFS | ||
|---|---|---|---|---|---|---|---|---|---|
| Potassium Oxanate (PO) | Mice Age (Months)/PO (Weeks) | IVSD | LVPWD | LVDD | LVDS | IVSD | LVPWD | LVDD | LVDS |
| ------ | 2 m/0 w | 0.82 ± 0.01 | 0.79 ± 0.01 | 1.98 ± 0.02 | 1.27 ± 0.03 | 0.81 ± 0.01 | 0.77 ± 0.01 | 1.98 ± 0.03 | 1.25 ± 0.03 |
| - | 3 m/4 w | 0.80 ± 0.02 | 0.76 ± 0.03 | 2.07 ± 0.11 | 1.27 ± 0.04 | 0.80 ± 0.02 | 0.78 ± 0.02 | 2.06 ± 0.04 | 1.36 ± 0.04 |
| - | 4 m/8 w | 0.87 ± 0.04 | 0.95 ± 0.09 | 1.88 ± 0.05 | 1.29 ± 0.08 | 0.95 ± 0.09 | 0.95 ± 0.09 | 2.31 ± 0.19 | 1.39 ± 0.05 |
| - | 6 m/16 w | 0.87 ± 0.03 | 0.85 ± 0.03 | 2.05 ± 0.07 | 1.40 ± 0.04 | 0.87 ± 0.01 | 0.83 ± 0.02 | 2.01 ± 0.03 | 1.32 ± 0.01 |
| + | 3 m/4 w | 0.83 ± 0.01 | 0.80 ± 0.002 | 2.03 ± 0.05 | 1.38 ± 0.02 | 0.82 ± 0.01 | 0.81 ± 0.01 | 2.07 ± 0.06 | 1.41 ± 0.04 |
| + | 4 m/8 w | 0.84 ± 0.04 | 0.93 ± 0.02 | 2.21 ± 0.19 | 1.43 ± 0.07 | 1.01 ± 0.05 | 1.06 ± 0.02 | 2.52 ± 0.07 | 1.71 ± 0.08 |
| + | 6 m/16 w | 0.79 ± 0.01 | 0.80 ± 0.02 | 2.11 ± 0.06 | 1.35 ± 0.04 | 0.79 ± 0.02 | 0.75 ± 0.03 | 2.00 ± 0.06 | 1.34 ± 0.02 |
IVSD: interventricular septum diameter; LVPWD: left ventricle posterior wall diameter; LVDD: left ventricle diameter in diastole; LVDS: left ventricle diameter in systole.