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Schematic representation of the in vitro sarcoidosis model to study human lung cells. Cells are isolated from lung tissue biopsy, BAL, or blood of sarcoidotic patients and healthy donors. In healthy controls without pulmonary pathology, bacterial agents (Mycobacterium protein particles, P. acnes) or carbon nanoparticles (MWNCTs) are added to initiate granulomas and pulmonary fibrosis as major signs of sarcoidosis.
