Table 2.
DRB1 allele carrier frequency in RA patients with or without CKD.
| CKD(+)RA (n = 351) | CKD(−)RA (n = 959) | p | OR | pc | 95%CI | |
|---|---|---|---|---|---|---|
| DRB1*01:01 | 54 (15.4) | 136 (14.2) | 0.5955 | 1.10 | NS | (0.78–1.55) |
| DRB1*03:01 | 1 (0.3) | 0 (0.0) | 0.2679 | 8.21 | NS | (0.33–202.08) |
| DRB1*04:01 | 19 (5.4) | 75 (7.8) | 0.1478 | 0.67 | NS | (0.40–1.13) |
| DRB1*04:03 | 10 (2.8) | 28 (2.9) | 1.0000 | 0.98 | NS | (0.47–2.03) |
| DRB1*04:04 | 3 (0.9) | 5 (0.5) | 0.4483 | 1.64 | NS | (0.39–6.92) |
| DRB1*04:05 | 162 (46.2) | 487 (50.8) | 0.1513 | 0.83 | NS | (0.65–1.06) |
| DRB1*04:06 | 11 (3.1) | 45 (4.7) | 0.2799 | 0.66 | NS | (0.34–1.29) |
| DRB1*04:07 | 3 (0.9) | 4 (0.4) | 0.3934 | 2.06 | NS | (0.46–9.24) |
| DRB1*04:10 | 16 (4.6) | 39 (4.1) | 0.7557 | 1.13 | NS | (0.62–2.04) |
| DRB1*07:01 | 2 (0.6) | 5 (0.5) | 1.0000 | 1.09 | NS | (0.21–5.66) |
| DRB1*08:02 | 18 (5.1) | 29 (3.0) | 0.0917 | 1.73 | NS | (0.95–3.16) |
| DRB1*08:03 | 26 (7.4) | 81 (8.4) | 0.6487 | 0.87 | NS | (0.55–1.37) |
| DRB1*09:01 | 102 (29.1) | 252 (26.3) | 0.3258 | 1.15 | NS | (0.88–1.51) |
| DRB1*10:01 | 5 (1.4) | 18 (1.9) | 0.8123 | 0.76 | NS | (0.28–2.05) |
| DRB1*11:01 | 10 (2.8) | 30 (3.1) | 0.8584 | 0.91 | NS | (0.44–1.88) |
| DRB1*12:01 | 21 (6.0) | 70 (7.3) | 0.4625 | 0.81 | NS | (0.49–1.34) |
| DRB1*12:02 | 9 (2.6) | 27 (2.8) | 1.0000 | 0.91 | NS | (0.42–1.95) |
| DRB1*13:01 | 0 (0.0) | 2 (0.2) | 1.0000 | 0.54 | NS | (0.03–11.38) |
| DRB1*13:02 | 34 (9.7) | 57 (5.9) | 0.0265 | 1.70 | 0.7412 | (1.09–2.64) |
| DRB1*14:02 | 1 (0.3) | 2 (0.2) | 1.0000 | 1.37 | NS | (0.12–15.12) |
| DRB1*14:03 | 6 (1.7) | 21 (2.2) | 0.6672 | 0.78 | NS | (0.31–1.94) |
| DRB1*14:05 | 7 (2.0) | 18 (1.9) | 0.8237 | 1.06 | NS | (0.44–2.57) |
| DRB1*14:06 | 19 (5.4) | 30 (3.1) | 0.0691 | 1.77 | NS | (0.98–3.19) |
| DRB1*14:07 | 1 (0.3) | 1 (0.1) | 0.4642 | 2.74 | NS | (0.17–43.88) |
| DRB1*14:54 | 27 (7.7) | 46 (4.8) | 0.0559 | 1.65 | NS | (1.01–2.70) |
| DRB1*15:01 | 37 (10.5) | 116 (12.1) | 0.4967 | 0.86 | NS | (0.58–1.27) |
| DRB1*15:02 | 56 (16.0) | 163 (17.0) | 0.6769 | 0.93 | NS | (0.67–1.29) |
| DRB1*16:02 | 5 (1.4) | 14 (1.5) | 1.0000 | 0.98 | NS | (0.35–2.73) |
| DR6 (DRB1*13, *14) | 93 (26.5) | 172 (17.9) | 0.0008 | 1.65 | (1.24–2.20) |
Allele carrier frequencies are shown in parentheses (%). Associations were tested by Fisher’s exact test using 2 × 2 contingency tables. RA: rheumatoid arthritis; CKD: chronic kidney disease; OR: odds ratio; CI: confidence interval; pc: corrected p.