Table 2.
Incidence rates and HRs of death-censored graft failure according to hypertension categories.
| Group | Number of participants | Graft failure | Follow-up Duration, Person-years | Incidence Rate, Per 1,000 person-years | Unadjusted, HR (95% CI) | Model 1, HR (95% CI)a | Model 2, HR (95% CI)b |
|---|---|---|---|---|---|---|---|
| Hypertension | |||||||
| No | 3,040 | 235 | 19,257 | 12.2 | 1 (reference) | 1 (reference) | 1 (reference) |
| Yes | 11,209 | 1,699 | 66,545 | 25.5 | 2.099 (1.831–2.406) | 2.085 (1.816–2.393) | 1.702 (1.481–1.956) |
| Hypertension categories | |||||||
| Normal BP | 2,260 | 170 | 14,537 | 11.7 | 1 (reference) | 1 (reference) | 1 (reference) |
| Elevated BP | 780 | 65 | 4,720 | 13.8 | 1.180 (0.886–1.570) | 1.190 (0.894–1.584) | 1.199 (0.900–1.596) |
| Incident HTN without medications | 2,949 | 349 | 18,431 | 18.9 | 1.622 (1.351–1.949) | 1.625 (1.351–1.953) | 1.464 (1.217–1.760) |
| Controlled HTN | 3,050 | 418 | 18,300 | 22.8 | 1.960 (1.640–2.342) | 1.969 (1.645–2.358) | 1.589 (1.326–1.905) |
| Uncontrolled HTN | 5,210 | 932 | 29,815 | 31.3 | 2.687 (2.282–3.165) | 2.708 (2.293–3.197) | 2.125 (1.797–2.513) |
BP, blood pressure; HR, hazard ratio; CI, confidential interval; SBP, systolic blood pressure; DBP, diastolic blood pressure; HTN, hypertension.
a
Model 1 was adjusted for age and sex.
b
Model 2 was adjusted for age, sex, low income, smoking, alcohol consumption, regular exercise, obesity, estimated glomerular filtration rate, and history of diabetes, cardiovascular disease and dyslipidemia.