Skip to main content
. 2023 Jul 18;9(7):583. doi: 10.3390/gels9070583

Table 1.

Regression coefficient (r2) value, msc, and diffusion exponent value (n) obtained from drug release profile of levofloxacin HCl-loaded Eudragit L-based ISG formulations fitting different mathematic equations.

Formula Zero Order First Order Higuchi’s Korsmeyer–PEPPAS
r2 msc r2 msc r2 msc r2 msc k ± SD n ± SD Release Mechanism
LLM10 0.8048 1.3742 0.8683 1.9759 0.9058 2.5144 0.9770 3.5961 3.344 ± 1.837 0.444 ± 0.050 Fickian diffusion
LLM15 0.7118 0.9164 0.8872 2.0854 0.8945 2.0844 0.9503 2.6867 2.603 ± 0.666 0.367 ± 0.028 Fickian diffusion
LLM20 0.7941 1.2387 0.9090 2.3402 0.9188 2.3419 0.9320 2.3732 1.856 ± 0.819 0.444 ± 0.055 Fickian diffusion