Figure 6.

The effect of lipid extract from microalga Nannochloropsis oceanica (0.003 mg/mL) on the expression of transcription factor Nrf2 and its main product (HO-1), its inhibitors (Keap1, Bach1, PGAM5) and its activators (p21, p62, KAP1, p38. MAPK) in keratinocytes. Four experimental groups were analyzed: control (not treated with the lipid extract or UVB), algae (exposed to the lipid extract for 24 h), UVB (exposed to UVB radiation (60 mJ/cm²)) and UVB + algae (exposed to UVB radiation and then treated with the lipid extract for 24 h). The data are expressed as a percentage relative to the control group and presented as mean values ± SD (n = 5 for each group). The statistically significant differences are denoted as follows: “x” indicates a comparison to the control group (control vs. all groups); “a” indicates a comparison to the algae group (all groups vs. the algae group); “b” indicates a comparison to the UVB group (all groups vs. the UVB). Groups with the same letter indicate significant differences between them (p < 0.05).