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. 2023 Jul 23;24(14):11825. doi: 10.3390/ijms241411825

Table 1.

Nerve Fiber Characteristics and Associated Pain.

Nerve Fiber Conduction Speed Diameter Myelination Type of Pain Pain Characteristics
A Delta Fast (5–30 m/s) Medium (2–5 μm) Myelinated Acute pain Sharp, pricking, or stabbing pain is often associated with acute injuries. Felt immediately following an injury and is usually localized to the area of injury. It can be described as “fast pain.”
A Beta Very fast (33–75 m/s) Large (5–20 μm) Myelinated Typically not associated with pain Generally responsible for transmitting non-painful stimuli such as touch, pressure, and proprioception. However, in nerve injury or disease cases, they may become involved in transmitting pain signals.
C Fibers Slow (0.5–2 m/s) Small (0.4–1.2 μm) Unmyelinated Chronic pain Dull, throbbing, aching, or burning pain is typically associated with chronic conditions. Felt a short while after an injury and can be widespread. It can be described as “slow pain”.