Pain |
An unpleasant sensory and emotional experience associated with actual or potential tissue damage or described in terms of such damage. |
Neuropathic Pain |
Pain caused by a lesion or disease of the somatosensory system. |
Central Neuropathic Pain |
Neuropathic pain resulting from a lesion or disease of the central somatosensory nervous system. |
Peripheral Neuropathic Pain |
Neuropathic pain resulting from a lesion or disease of the peripheral somatosensory nervous system. |
Nociceptive Pain |
Pain that arises from actual or threatened damage to non-neural tissue and is due to the activation of nociceptors. |
Nociplastic Pain |
Pain that arises from altered nociception despite no clear evidence of actual or threatened tissue damage. |
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Types of Pain Sensations:
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Allodynia |
Pain due to a stimulus that does not normally provoke pain. |
Hyperalgesia |
An increased response to a stimulus which is normally painful. |
Hypoalgesia |
Decreased sensitivity to painful stimuli. |
Anesthesia dolorosa |
Pain in an area or region which is anesthetic. |
Dysesthesia |
An unpleasant abnormal sensation, whether spontaneous or evoked. |
Hyperesthesia |
Increased sensitivity to stimulation, excluding the special senses. |
Hyperpathia |
A painful syndrome characterized by an abnormally painful reaction to a stimulus, especially a repetitive stimulus, as well as an increased threshold. |
Hypoesthesia |
Decreased sensitivity to stimulation, excluding the special senses. |
Paresthesia |
An abnormal sensation, whether spontaneous or evoked. |
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Nerve-Related Terms:
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Neuralgia |
Pain in the distribution of a nerve or nerves. |
Neuritis |
Inflammation of a nerve or nerves. |
Neuropathy |
A disturbance of function or pathological change in a nerve. |
Nociception |
The neural process of encoding noxious stimuli. |
Nociceptive Neuron |
A neuron that is capable of detecting noxious stimuli. |
Nociceptive Stimulus |
A stimulus that is damaging or threatens damage to normal tissues. |
Nociceptor |
A receptor preferentially sensitive to a noxious stimulus or to a stimulus which would become noxious if prolonged. |
Noxious Stimulus |
A stimulus that is damaging to normal tissues. |
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Pain Threshold and Tolerance:
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Pain Threshold |
The minimum intensity of a stimulus that is perceived as painful. |
Pain Tolerance Level |
The maximum level of pain which a subject is prepared to tolerate. |
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Sensitization: |
Sensitization |
An increased response to stimulation. |
Central Sensitization |
Increased responsiveness of nociceptive neurons in the central nervous system to their normal or subthreshold afferent input. |