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. 2023 Jul 19;24(14):11660. doi: 10.3390/ijms241411660

Figure 8.

Figure 8

The transcriptome response of MDA-MB-231 cells to 100 nM-24 h Doxorubicin (DOX) treatment sampled on day 5: (A) The STRING network of upregulated genes (green-marked) in the 8th phylostratum; ten of them belonging to the ‘female pregnancy’ module (GO: 0007565) are coloured red and occupy central positions in the network. (B) The DOX-upregulated gene phylostratigraphic distribution (green bars against the red-lined whole-genome reference) showing the strong activation of Str 8 via DOX. (C) The “female pregnancy module” upregulated genes (log-folds). (B) Republished from Ref. [20], CC BY 4.0 licence.