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Clearance of rhADAMTS-13 in mouse circulation: blood was collected from the eyes 6, 24, and 48 h after rhADAMTS-13 infusion. Plasma levels of the metalloprotease were measured by capturing ELISA (n = 6, one-way ANOVA, * p < 0.05, compared to the value measured 6 h post-ADAMTS-13 infusion) and immunoblots (insert, n = 4).
