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. 2023 Jul 24;24(14):11860. doi: 10.3390/ijms241411860

Figure 6.

Figure 6

(A) LXR activation has little effect on blocking S protein pseudovirion infection of ARPE-19 cells. Fold difference in uptake of original spike-pseudotyped lentiviruses at MOI 10 in the presence of 100 nM–10 μM concentrations of the synthetic LXR agonist GW3965 at 48 h compared to untreated controls infected with original spike protein pseudotyped particles alone. (B) GW3965 is toxic at the highest 10 μM concentration: % Cell viability at 100 nM–10 μM concentrations of GW3965 measured by MTT assay. ** p  <  0.001, **** p < 0.0001.