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. 2023 Jul 24;24(14):11860. doi: 10.3390/ijms241411860

Figure 15.

Figure 15

(A). Overexpression of LDLR in hLDLR-HeLa cells significantly increases S protein pseudovirion infection of ARPE-19 cells (p < 0.0005). The graph shows the fold difference in the uptake of original spike-pseudotyped lentiviruses in HeLa cells compared to stably expressing hLDLR-HeLa cells. *** p <  0.0005. (B) GFP fluorescence (green) analysis of infected hLDLR-HeLa (top panels) and HeLa cells (bottom panels) with Expi293-produced original SARS-CoV-2 spike pseudovirions, Hoechst nuclear staining (blue), bright field image, and overlay of all three images (from left to right). 4× magnification and scale bar: 180 µm.