| mTOR | mechanistic target of rapamycin; |
| RAPTOR | regulatory-associated protein of mTOR; |
| RICTOR | rapamycin-insensitive companion of mTOR; |
| DEPTOR | DEP domain-containing mTOR-interacting protein; |
| mLST8 | mammalian lethal with SEC13 protein 8; |
| PRAS40 | proline-rich AKT substrate of 40 kDa; |
| mSIN1 | mammalian stress-activated protein kinase-interaction protein 1; |
| PROTOR | protein observed with RICTOR; |
| TSC1/2 | tuberous sclerosis complex 1/2; |
| RHEB | Ras homolog mTORC1 binding; |
| RAGs | Ras-related GTPases; |
| IRS | insulin receptor substrate; |
| PI3K | phosphoinositide 3-kinase; |
| PIP3 | phosphatidylinositol 3,4,5-triphosphate; |
| PTEN | phosphatase and tensin homolog; |
| PDK1 | phosphoinositide-dependent protein kinase 1; |
| GRB10 | growth factor receptor bound protein 10; |
| AKT; | protein kinase B; |
| ERK | extracellular signal-regulated kinase; |
| RSK | ribosomal S6 kinase 1; |
| TNF | tumor necrosis factor; |
| IKKβ | inhibitor of nuclear factor kappa-B kinase subunit beta; |
| AMPK | AMP-activated protein kinase; |
| WNT | wingless and lnt-1; |
| GSKβ | glycogen synthase kinase 3β; |
| REDD1 | regulated in development and DNA damage responses 1; |
| p38 MAPK | p38 mitogen-activated protein kinases; |
| MK2 | MAPK activated protein kinase 2; |
| ROS | reactive oxygen species; |
| NO | nitric oxide; |
| ANP | atrial natriuretic peptide; |
| BNP | B-type natriuretic peptide; |
| GPCR | G protein-coupled receptor; |
| GC | guanylyl cyclase; |
| sGC | soluble guanylyl cyclase; |
| cAMP | cyclic adenosine monophosphate; |
| cGMP | cyclic guanosine monophosphate; |
| PKA | cAMP-dependent protein kinase; |
| PKG | cGMP-dependent protein kinase; |
| SIK3 | salt-inducible kinase 3; |
| FKBP12 | FK506-binding protein of 12 kDa; |
| PIP2 | phosphatidylinositol 4,5-bisphosphate |
| PKA | protein kinase A; |
| PKG | protein kinase G; |
| GPCRs | G protein-coupled receptors; |
| EPAC | exchange protein directly activated by cAMP (EPAC); |
| LKB1 | liver kinase B1; |
| PDE | phosphodiesterase; |
| NPs | natriuretic peptides; |
| TBG | thyroxine binding globulin; |
| TAC | transverse aortic constriction; |
| MHC | α-myosin heavy chain; |
| MI | myocardial infarction; |
| IBMX | 3-Isobutyl-1-methylxanthine; |
| MEFs | Mouse embryonic fibroblast; |
| PTH/PTHrP | parathyroid hor-mone/PTH-related peptide; |
| GLP-1 | Glucagon-like peptide-1; |
| GLP-1RA | GLP-1 receptor agonist; |
| KATP channels | ATP-sensitive K+ channels; |
| TSH | thyroid-stimulating hormone; |
| hCG | human chorionic gonadotropin; |
| β-AR | β-adrenergic receptor; |
| NRVMs | neonatal rat ventricular myocytes; |
| ER | endoplasmic reticulum; |
| GPCRs | G protein-coupled receptors. |
| DNL | de novo lipogenesis; |
| NAFLD | nonalcoholic fatty liver disease; |
| NAFL | nonalcoholic fatty liver; |
| NASH | nonalcoholic hepatic steatosis; |
| HCC | hepatocellular carcinoma; |
| UCP1 | uncoupling protein 1; |
| WAT | white adipose tissue. |