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. 2023 Jul 15;24(14):11497. doi: 10.3390/ijms241411497
mTOR mechanistic target of rapamycin;
RAPTOR regulatory-associated protein of mTOR;
RICTOR rapamycin-insensitive companion of mTOR;
DEPTOR DEP domain-containing mTOR-interacting protein;
mLST8 mammalian lethal with SEC13 protein 8;
PRAS40 proline-rich AKT substrate of 40 kDa;
mSIN1 mammalian stress-activated protein kinase-interaction protein 1;
PROTOR protein observed with RICTOR;
TSC1/2 tuberous sclerosis complex 1/2;
RHEB Ras homolog mTORC1 binding;
RAGs Ras-related GTPases;
IRS insulin receptor substrate;
PI3K phosphoinositide 3-kinase;
PIP3 phosphatidylinositol 3,4,5-triphosphate;
PTEN phosphatase and tensin homolog;
PDK1 phosphoinositide-dependent protein kinase 1;
GRB10 growth factor receptor bound protein 10;
AKT; protein kinase B;
ERK extracellular signal-regulated kinase;
RSK ribosomal S6 kinase 1;
TNF tumor necrosis factor;
IKKβ inhibitor of nuclear factor kappa-B kinase subunit beta;
AMPK AMP-activated protein kinase;
WNT wingless and lnt-1;
GSKβ glycogen synthase kinase 3β;
REDD1 regulated in development and DNA damage responses 1;
p38 MAPK p38 mitogen-activated protein kinases;
MK2 MAPK activated protein kinase 2;
ROS reactive oxygen species;
NO nitric oxide;
ANP atrial natriuretic peptide;
BNP B-type natriuretic peptide;
GPCR G protein-coupled receptor;
GC guanylyl cyclase;
sGC soluble guanylyl cyclase;
cAMP cyclic adenosine monophosphate;
cGMP cyclic guanosine monophosphate;
PKA cAMP-dependent protein kinase;
PKG cGMP-dependent protein kinase;
SIK3 salt-inducible kinase 3;
FKBP12 FK506-binding protein of 12 kDa;
PIP2 phosphatidylinositol 4,5-bisphosphate
PKA protein kinase A;
PKG protein kinase G;
GPCRs G protein-coupled receptors;
EPAC exchange protein directly activated by cAMP (EPAC);
LKB1 liver kinase B1;
PDE phosphodiesterase;
NPs natriuretic peptides;
TBG thyroxine binding globulin;
TAC transverse aortic constriction;
MHC α-myosin heavy chain;
MI myocardial infarction;
IBMX 3-Isobutyl-1-methylxanthine;
MEFs Mouse embryonic fibroblast;
PTH/PTHrP parathyroid hor-mone/PTH-related peptide;
GLP-1 Glucagon-like peptide-1;
GLP-1RA GLP-1 receptor agonist;
KATP channels ATP-sensitive K+ channels;
TSH thyroid-stimulating hormone;
hCG human chorionic gonadotropin;
β-AR β-adrenergic receptor;
NRVMs neonatal rat ventricular myocytes;
ER endoplasmic reticulum;
GPCRs G protein-coupled receptors.
DNL de novo lipogenesis;
NAFLD nonalcoholic fatty liver disease;
NAFL nonalcoholic fatty liver;
NASH nonalcoholic hepatic steatosis;
HCC hepatocellular carcinoma;
UCP1 uncoupling protein 1;
WAT white adipose tissue.