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Effect of NP-2007 on matrix metalloproteinase (MMP) production in serum of MIA-induced OA rats. (A) MMP-2, (B) MMP-3, and (C) MMP-9 production were measured using enzyme-linked immunosorbent assays (ELISAs). All values represent the mean ± SD (n = 7). Data were examined using Duncan’s multiple comparison test. ** p < 0.01 and *** p < 0.001 vs. control group; # p < 0.05, ## p < 0.01, and ### p < 0.001 vs. MIA-injected group.
