Figure 2.

(a) Counts of structures containing water molecules resolved by different methods and deposited in the Protein Data Bank. Data were collected by the advanced search module of the PDB database: Entry features > Number of water molecules per deposited model. The number of structures was automatically separated by methods used for resolving. (b) The number of water-containing cryo-EM structures resolved in 5-year-long periods of time. The number on the x axis indicates the last year of the period.