Table 2.
Cell growth percentagesa after 72 h of exposure to 10 μM of the most active compounds 3b, 3e, 4c, 5b, 6c.
PDAC Cell Lines |
1,3,4-Oxadiazoles | 1,3,4-Thiadiazoles | |||
---|---|---|---|---|---|
3b | 3e | 4c | 5b | 6c | |
BxPC-3 | 11.10 | 58.64 | 21.13 | 32.88 | 54.59 |
Panc-1 | 9.12 | 61.96 | 74.33 | 15.68 | 83.68 |
Panc-1-GR | 22.47 | >100 | 98.62 | 40.65 | >100 |
Suit-2 | 18.34 | 54.94 | 60.18 | 19.46 | 29.80 |
Capan-1 | 18.33 | 59.84 | 75.17 | 30.86 | 76.76 |
PaTu-T | 17.13 | 72.33 | 31.22 | 27.73 | 56.09 |
PDAC-3 | 38.35 | >100 | 96.60 | 55.90 | 87.84 |
a Data were expressed as mean values of three replicates.