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. 2023 Jul 18;12(14):4759. doi: 10.3390/jcm12144759

Table 2.

Comparison of the general condition according to periodontal status.

PISA [mm2] < 300 PISA [mm2] ≧ 300 p-Value
Age [years] 69 (50, 75) 71.5 (58, 79) 0.48
Sex [female %] 55.5 10.4 0.07
Number of teeth 25 (22, 27) 26 (22, 28) 0.40
HbA1c [%] 5.6 (5.4, 5.9) 5.8 (5.4, 6.4) 0.24
Blood glucose [mg/dL] 110 (98, 127) 112 (99, 175) 0.25
Probing depth [mm] 2.2 (2.0, 2.4) 3.0 (2.5, 3.3) <0.0001
Bleeding on probing [%] 14 (8, 23) 47 (35, 62) <0.0001
Leukocyte score in saliva 59 (35, 77) 77 (70, 89) <0.0001
Protein score in saliva 42 (28, 65) 58 (43, 83) 0.0001
Increased AST [%] 48.2 52.9 0.62
Increased ALT [%] 35.3 47.0 0.20
Increased GGT [%] 10.8 29.4 0.0056

The subjects were divided into two groups according to the PISA using a cutoff value of 300 mm2. Cutoff values were also established for AST, ALT, and GGT; more than 20 U/L of AST, more than 20 U/L of ALT, and more than 50UI GGT were judged as high values. PISA, periodontal inflamed surface area; HbA1c, hemoglobin A1c; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase.