Table 1.
Salient characteristics of the study population. Quantitative variables are presented as medians (interquartile range). HOMA-IR = Homeostasis Model Assessment-Insulin resistance, ALP = Alkaline phosphatase, GGT = Ɣ-glutamyl transferase, ALT = alanine transferase, LDL= low density lipoprotein.
| Controls (n = 521) | HS (n = 111) | p Value | |
|---|---|---|---|
| N (%) Female | 330 (63.3%) | 54 (48.6%) | <0.01 |
| N (%) Smokers/Ex-smokers | 165 (31.7%) | 71 (64%) | <0.01 |
| Metabolic Syndrome (NCEP-ATPIII) | 88 (20.3%) | 36 (32.4%) | <0.001 |
| N (%) Type 2 Diabetes | 23 (4.6%) | 8 (7.2%) | 0.178 |
| N (%) Hurley I | - | 53 (47.7%) | |
| N (%) Hurley II | - | 41 (36.9%) | |
| N (%) Hurley III | - | 17 (15.3%) | |
| Age years | 41 (6) | 34 (25) | <0.001 |
| Body Mass Index kg/m2 | 27.5 (7.8) | 31 (10.8) | <0.001 |
| Waist Circumference cm | 89 (20) | 100 (25) | <0.001 |
| Systolic Blood Pressure mmHg | 120 (10) | 133 (23) | <0.001 |
| Diastolic Blood pressure mmHg | 80 (10) | 79.5 (16) | 0.488 |
| Fasting plasma glucose mmol/L | 5.13 (0.66) | 5.06 (0.9) | 0.472 |
| HOMA-IR | 1.65 (1.17) | 1.83 (1.24) | 0.031 |
| HbA1c % | 5.3 (0.4) | 5.3 (0.6) | 0.126 |
| ALP U/L | 63 (21) | 72 (33) | <0.001 |
| GGT U/L | 19 (16) | 23 (22) | 0.05 |
| ALT U/L | 17 (13) | 16 (12) | 0.185 |
| Total Cholesterol mmol/L | 4.87 (1.1) | 4.73 (1.66) | 0.749 |
| LDL-C mmol/L | 2.85 (1.06) | 3 (1.43) | 0.326 |
| HDL-C mmol/L | 1.41 (0.49) | 1.27 (0.52) | <0.001 |
| Triglycerides mmol/L | 1.01 (0.71) | 1.11 (0.73) | 0.067 |
| Visceral Adiposity Index | 1.09 (1.1) | 1.31 (1.49) | 0.01 |
| Atherogenic Index of Plasma | −0.16 (0.42) | −0.08 (0.45) | 0.013 |
| Platelet lymphocyte ratio | 134.39 (62.25) | 135.29 (73.5) | 0.604 |
| Neutrophil lymphocyte ratio | 2.02 (0.89) | 2.34 (0.99) | 0.001 |
| Red cell distribution width % | 14.62 (2.48) | 15.91 (2.77) | <0.001 |