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. 2023 Jul 23;12(14):4849. doi: 10.3390/jcm12144849

Table 3.

Assessment of the CSI cutoff scores for the total group and per sex, comparing patients with CSS+ and healthy volunteers.

Total Group (N = 1730) vs. Healthy Volunteers (N = 250);
AUC: 0.953
Cutoff Score Youden Index Sensitivity Specificity
28 0.7775 0.8855 0.8920
29 0.7785 0.8705 0.9080
30 0.7818 0.8538 0.9280
31 0.7701 0.8341 0.9360
32 0.7648 0.8208 0.9440
Women (N = 1213) vs. Healthy Female Volunteers (N = 157)
AUC: 0.956
Cutoff Score Youden Index Sensitivity Specificity
30 0.7913 0.8805 0.9108
31 0.7851 0.8615 0.9236
32 0.7782 0.8483 0.9299
33 0.7934 0.8252 0.9682
34 0.7736 0.8054 0.9682
35 0.7505 0.7824 0.9682
Men (N = 517) vs. Healthy Male Volunteers (N = 93)
AUC: 0.947
Cutoff Score Youden Index Sensitivity Specificity
23 0.7497 0.9110 0.8387
24 0.7674 0.9072 0.8602
25 0.8037 0.8897 0.9140
26 0.7883 0.8743 0.9140
27 0.7708 0.8569 0.9140

Abbreviations: N: number; CSI: central sensitization inventory; CSS: central sensitivity syndromes; AUC: area under the curve. Statistics: ROC analyses were used to calculate AUC, sensitivity and specificity, and the Youden index.