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. 2023 Jul 12;13(7):1543. doi: 10.3390/life13071543

Table 1.

Differences in thrombosis due to atherosclerotic plaque rupture or erosion.

Erosion Rupture
Fibrous cap Thick and intact Thin, fissured
Thrombus “White”
Rich in platelets
“Red”
Rich in fibrin
Mechanism of activation Collagen Tissue factor
Prevailing cells Smooth muscle cells Macrophages
Remodeling Lower degree, outward remodeling Marked positive remodeling
NET presence ++ +/±
Common clinical outcome Non-STEMI STEMI

NET: neutrophil extracellular trap; STEMI: ST-segment elevation myocardial infarction.