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. 2023 Jun 2;12(11):e029512. doi: 10.1161/JAHA.123.029512

Figure 3. Dose–response relationship between changes in lipids and combined intake of DHA + EPA of studies stratified by hyperlipidemia status.

Figure 3

Marginal average dose–response curve (solid line) with 95% point‐wise CIs (dashed lines) estimated by a 1‐stage random‐effects restricted cubic spline model, using 0 g/day as reference, in participants with or without hyperlipidemia. n=the number of the included study. DHA indicates docosahexaenoic acid; EPA, eicosapentaenoic acid; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; and TG, triglyceride.