Figure 5. Dose–response relationship between changes in lipids and combined intake of DHA + EPA of the studies stratified by overweight/obesity classified by the baseline mean of body mass index (BMI).

Marginal average dose–response curve (solid line) with 95% point‐wise CIs (dashed lines) estimated by a 1‐stage random‐effects restricted cubic spline model, using 0 g/day as reference, among participants with a mean BMI ≥25 or <25 kg/m². n=the number of the included study. BMI indicates body mass index; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; HDL‐C, high‐density lipoprotein cholesterol; LDL‐C, low‐density lipoprotein cholesterol; and TG, triglyceride.