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. 2023 Jun 1;12(11):e029218. doi: 10.1161/JAHA.122.029218

Figure 5. Interleukin‐17a neutralization reduces OSA‐induced gut and neuroinflammation.

Figure 5

Effects of interleukin‐17a neutralization on Tregs, TH1, TH17, TNFα+, and macrophages in the ileum (A), cecum (B), and brain (C) of sham and OSA rats. n=4 in ileum, n=6 in cecum and brain; *P<0.05, **P<0.005, ***P<0.0005, ****P<0.0001 using 2‐way ANOVA with Tukey's multiple comparisons test. Error bars represent ±SEM. OSA indicates obstructive sleep apnea; TH, T helper cell; and Tregs, T regulatory cells.