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The increase in n-6/n-3 PUFAs ratio in ageing rats was effectively reversed by EPA and DHA. The contents of n-3 PUFAs EPA (A), DPA (B), and DHA (C) and contents of n-6 PUFAs cis-8,11,14-eicosatrienoic acid (D) and AA (E) as well as n-6/n-3 PUFAs ratio (F). The data were expressed as mean ± SEM (n = 5). * p < 0.05, ** p < 0.01 versus control group; # p < 0.05, ### p < 0.001 versus ageing group. & p < 0.05 versus ageing + EPA group.
