TABLE 4.

Summary of serological, clinical, and ASC data

Group no.a	VN on PID 0bc	Postinoculationd		PID 21ef					Postchallenged		PCD 7e
		% of pigs with diarrheag	% of pigs shedding virush	VNc	IgA ASC		IgG ASC		% of pigs with diarrhea	% of pigs shedding virus	IgA ASC		IgG ASC
					Di	Ij	D	I			D	I	D	I
1	1,566 A	23 B	64 B	684 A	11*	7*	9*	14*	42 A, B	17 A	25*▵	20*▵	13*	51▵
2	1,792 A	33 B	50  B	543 A, B	0*	1*	0*	3*	60 A	20 A	1*	1*	3*	1*
3	17 B	100 A	100 A	305 B, C	48	39	29□	77	25 A, B	0 A	57	35	15*	85
4	11 B	91 A	73  B	190 C	27	22	15	111	33 A, B	17 A	39	25	16*	35
5	<4 C	95 A	100 A	79 D	40	66	52	76	12 B	0 A	94	43	56	56

^aFor an explanation of groups, see Table 1, footnote i. 

^bVN, VN GMT. 

^cMeans in these columns followed by different letters differ significantly (one-way ANOVA; log-transformed titers). 

^dProportions in these columns followed by different letters differ significantly (Fisher’s exact test). 

^eSymbols: *, group differed significantly from group 5 for the same isotype at the same time point (Kruskal-Wallis rank sum test); ▵, groups 1 and 2 differed significantly for the same isotype at the same time point (Kruskal-Wallis rank sum test); □, groups 3 and 4 differed significantly for the same isotype at the same time point (Kruskal-Wallis rank sum test). 

^fPID 21 = day of challenge. 

^gFeces were scored as follows: 0, normal; 1, pasty; 2, semiliquid; 3, liquid; feces with a score of ≥2 was considered diarrheic. 

^hDetermined by ELISA and CCIF infectivity assay. 

ⁱD, duodenum. 

^jI, ileum.