TABLE 5.
Mean IgSC counts in intestinal and systemic tissues
Time | Exptl group | ng | No. of IgSCe
|
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---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Duodenum
|
Ileum
|
MLN
|
Spleen
|
PBLf
|
|||||||||||||
IgM | IgA | IgG | IgM | IgA | IgG | IgM | IgA | IgG | IgM | IgA | IgG | IgM | IgA | IgG | |||
PID 8 | No maternal antibodiesa | 0 | NAd | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Serumb | 8 | 1,879 | 779 A | 688 A | 1,711 | 921 A | 929 A | 79 | 116 A | 93 A | 856 A | 388 A | 113 A | 26 | 19 | 39 | |
Serum + colostrum/milkc | 4 | 409 | 100 B | 0 B | 462 | 98 B | 0 B | 54 | 6 B | 1 B | 32 B | 1 B | 1 B | 32 | 5 | 1 | |
PID 21 | No maternal antibodies | 6 | 7 B | 1,275 A | 460 | 0 B | 2,412 A | 1,157 A | 0 B | 173 | 347 | 1 B | 54 | 42 | 0 B | 122 | 18 |
Serum | 8 | 445 A | 1,724 A | 1,027 | 323 A | 1,682 A | 739 A | 86 A | 248 | 134 | 65 A | 86 | 145 | 46 A | 84 | 99 | |
Serum + colostrum/milk | 4 | 14 A, B | 242 B | 67 | 35 A | 358 B | 208 B | 103 A | 155 | 100 | 73 A | 59 | 30 | 20 A | 18 | 15 | |
PID 25/PCD 4 | No maternal antibodies | 4 | 74 | 194 B | 379 | 25 B | 669 A, B | 609 | 4 C | 155 B | 237 | 2 B | 36 B | 52 | 1 B | 71 | 29 |
Serum | 9 | 445 | 5,147 A | 368 | 889 A | 3,456 A | 983 | 86 B | 349 A | 142 | 39 B | 74 A | 102 | 39 B | 83 | 121 | |
Serum + colostrum/milk | 4 | 274 | 893 A, B | 59 | 1,541 A | 344 B | 320 | 1,544 A | 504 A | 177 | 565 A | 235 A | 114 | 448 A | 121 | 73 | |
PID 28/PCD 7 | No maternal antibodies | 3 | 11 | 191 | 97 | 8 | 200 B | 77 | 6 B | 31 B | 57 | 2 | 4 B | 2 B | 0 B | 47 | 11 |
Serum | 10 | 257 | 1,654 | 711 | 381 | 1,789 A | 2,040 | 63 A | 828 A | 426 | 30 | 321 A | 215 A | 10 B | 125 | 258 | |
Serum + colostrum/milk | 4 | 201 | 3,176 | 280 | 65 | 381 B | 305 | 78 A | 449 A, B | 343 | 48 | 363 A | 185 A | 41 A | 219 | 149 |
No maternal antibodies: group 5 pigs.
Serum: data from group 1 and group 3 pigs were pooled to examine the effects of administration of serum on total IgSC numbers.
Serum + colostrum/milk: data from group 2 and group 4 pigs were pooled to examine the effects of administration of serum, colostrum, and milk on total IgSC numbers.
NA, not available.
Values for the different Igs are mean numbers of IgSC per 5 × 105 MNC. Means in the same column at the same time point followed by different letters differ significantly (Kruskal-Wallis rank sum test [nonparametric]).
PBL, peripheral blood lymphocyte.
Number of pigs euthanatized in each group at each time point.