Table 2.

The intersection of top 50 drugs by activity (Method 1) and connectivity (Method 2) scores on FOXM1 pathway.

Drug name	Dose (µM)	Na	Rank by		Activity score (Method 1)			Connectivity score (Method 2)
			Activity score difference (ASd)b	Connectivity score	Treatment (ASt)	Control (ASc)	Difference (ASd)
5109870	25	1	1	10	−8.57	1.59	−10.16	−0.66
MG-132	21	1	2	1	−4.45	1.97	−6.42	−1
MG-262	0.1	1	4	3	−2.95	1.79	−4.74	−0.83
Celastrol	2.5	1	5	7	−2.99	1.59	−4.58	−0.72
Resveratrol	50	2	6	8	0.92	5.2	−4.28	−0.7
Ciclopirox	15	2	7	37	−2.45	1.53	−3.98	−0.59
Pyrvinium	3.4	2	11	2	−1.85	1.56	−3.41	−0.84
Emetine	7.2	2	13	14	−1.37	1.71	−3.08	−0.63
15-delta prostaglandin J2	10	8	14	11	−1.18	1.73	−2.91	−0.66
Cephaeline	6	3	15	32	−0.95	1.96	−2.91	−0.6
Puromycin	7.4	2	16	17	−0.94	1.89	−2.84	−0.62
Parthenolide	16.2	2	23	18	−1.43	1.03	−2.46	−0.62
Azacitidine	16.4	2	24	49	−0.87	1.53	−2.39	−0.57
Cycloheximide	14.2	2	28	45	−0.3	2	−2.29	−0.57
Astemizole	8.8	2	29	27	0.04	2.3	−2.26	−0.6
5224221	12	2	36	25	−1.42	0.61	−2.03	−0.6
Scriptaid	10	1	42	20	1.32	3.29	−1.97	−0.62
Ouabain	5.4	2	43	30	−0.34	1.63	−1.97	−0.6
Bepridil	10	2	49	13	0.12	2	−1.88	−0.63

^aThe number of experiments.

^bActivity difference (ASd) = activity score in treatment (ASt) − activity score in control (ASc).