Table 2.
Vascular FAPI uptake
| Carotid arteries | Ascending aorta | Aortic arch | Descending thoracic aorta | Abdominal aorta | Iliac arteries | Femoral arteries | All vessels | |
|---|---|---|---|---|---|---|---|---|
| Number (%) of patients with vessel wall associated FAPI uptake | 16 (23.2) | 12 (17.4) | 42 (60.9) | 58 (84.1) | 61 (88.4) | 45 (65.2) | 25 (36.2) | 64 (92.8) |
| Total number of uptake sites | 24 | 18 | 81 | 294 | 239 | 105 | 39 | 800 |
| Sites with concomitant calcification n (%) | 21 (87.5) | 7 (38.9) | 38 (46.9) | 70 (23.8) | 143 (59.8) | 71 (67.6) | 27 (69.2) | 377 (47.1) |
| SUVmax | ||||||||
| Mean ± SD | 2.6 ± 0.6 | 2.9 ± 0.9 | 2.9 ± 0.8 | 3.1 ± 0.9 | 2.9 ± 0.9 | 2.9 ± 0.9 | 2.5 ± 0.6 | 2.9 ± 0.9 |
| Range | 1.8–4.4 | 1.7–5.6 | 1.7–6.5 | 1.5–7.8 | 1.3–7.1 | 1.5–5.4 | 1.4–3.9 | 1.3–7.8 |
| TBR | ||||||||
| Mean ± SD | 2.2 ± 0.5 | 2.5 ± 0.6 | 2.5 ± 0.6 | 2.6 ± 0.6 | 2.5 ± 0.7 | 2.5 ± 0.7 | 2.3 ± 0.5 | 2.5 ± 0.6 |
| Range | 1.6–3.8 | 1.6–3.9 | 1.6–4.6 | 1.6–5.0 | 1.6–5.8 | 1.6–5.8 | 1.6–3.4 | 1.6–5.8 |
| SUVmean blood-pool | ||||||||
| Mean ± SD | 1.2 ± 0.2 | |||||||
| Range | 0.7–1.9 | |||||||
FAPI, fibroblast activation protein inhibitor; SUV, standardized uptake value; TBR, target-to-background ratio; SUVmean blood pool, mean standardized uptake value derived from the mean of three regions of interest of at least 10 mm diameter on non-adjacent slices within the mid lumen of the superior vena cava serving as reference tissue for TBR calculations