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. 2023 Jun 1;50(10):3050–3061. doi: 10.1007/s00259-023-06272-7

Table 3.

[177Lu]Lu-FAPI-46-Ibu biodistribution results HT-1080 and HEK-293 xenografts expressed as mean of the % injected activity per gram of tissue (%I.A./g) ± standard deviation (SD) (n = 4/group)

Organ HT-1080 HEK-293
4 h 24 h 72 h 4 h 24 h 72 h
Blood 1.07 ± 0.10 0.14 ± 0.03 0.01 ± 0.00 1.00 ± 0.18 0.10 ± 0.01 0.00 ± 0.00
Lung 0.83 ± 0.07 0.21 ± 0.03 0.07 ± 0.02 1.88 ± 2.29 0.15 ± 0.01 0.04 ± 0.01
Liver 0.96 ± 0.08 1.02 ± 0.70 0.50 ± 0.02 0.75 ± 0.11 0.58 ± 0.35 0.35 ± 0.04
Kidney 1.80 ± 0.15 1.15 ± 0.19 0.54 ± 0.11 1.33 ± 0.17 0.81 ± 0.11 0.25 ± 0.03
Muscle 0.97 ± 0.25 0.43 ± 0.28 0.12 ± 0.07 0.87 ± 0.36 0.28 ± 0.08 0.07 ± 0.03
Femur 3.62 ± 0.04 1.12 ± 0.12 0.51 ± 0.09 2.46 ± 0.88 0.81 ± 0.11 0.33 ± 0.08
hFAP-tumor 8.40 ± 1.97 5.09 ± 0.64 1.55 ± 0.58 5.03 ± 2.84 3.14 ± 0.49 0.88 ± 0.40
wt-tumor 1.96 ± 0.36 1.00 ± 0.25 0.28 ± 0.05 1.86 ± 1.25 0.52 ± 0.11 0.18 ± 0.05