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. 2023 Apr 5;13(9):2315–2339. doi: 10.1007/s13346-023-01315-w

Table 3.

Optimized formulation as suggested by software together with the expected and observed results

PC:VA molar ratio Precursor concentration (mg/mL) PS (nm) PDI ZP (mV)
Expected result 1.3: 1 53.164 278.928 0.312 -25
Observed result 229.7 ± 3.76 0.29 ± 0.07 -30.8 ± 1.87
*%bias 21.43% 7.05% 23.20%