Table 3.

Safety details according to patients’ age.

Toxicity	≥ 75 years, n (%)	< 75 years, n (%)
Tot patients	N = 112	N = 472
Hematologic	27 (24.1)	93 (19.7)
G1-2	18 (16.1)	66 (13.9)
G3-4	9 (8.03)	27 (5.7)
Nausea/vomiting	15 (13.4)	90 (19.1)
G1-2	12 (10.7)	81 (17.2)
G3-4	3 (2.7)	9 (1.9)
Diarrhea	14 (12.5)	65 (13.8)
G1-2	12 (10.7)	61 (12.9)
G3-4	2 (1.8)	4 (0.8)
Fatigue	13 (11.6)	53 (11.2)
G1-2	11 (9.8)	50 (10.6)
G3-4	2 (1.8)	3 (0.6)
Cutaneous	8 (7.1)	60 (12.7)
G1-2	7 (6.3)	47 (9.9)
G3-4	1 (0.9)	13 (2.7)
Hepatic	5 (4.5)	38 (8.0)
G1-2	3 (2.7)	32 (6.8)
G3-4	2 (1.8)	6 (1.3)
Other toxicity	11 (9.8)	61 (12.9)
G1-2	7 (63.6)	55 (90.2)
G3-4	4 (36.4)	6 (9.8)