Table 3.

Molecular docking scores of the bacterial quorum sensing pathway proteins SecA-SecY, LsrR, PqsR (MvfR), AgrA interaction via curcumin and ciprofloxacin, as the docked compounds.

Bacterial protein	Organism	PDB ID	Ligand compound	Binding affinity (kcal/mol)
SecA-SecY	B. subtilis	6itc	Curcumin	− 6.6
			Ciprofloxacin	− 5.5
LsrR	E. coli	4l5j	Curcumin	− 5.5
			Ciprofloxacin	− 4.3
PqsR (MvfR)	P. aeruginosa	6yiz	Curcumin	− 7.8
			Ciprofloxacin	− 6.4
AgrA	S. aureus	4g4k	Curcumin	− 6.0
			Ciprofloxacin	− 5.11