Table 2.

Clinical characteristics of nodule number and nodule echo in thyroid nodule participants.

Parameter	Number of nodules		p	Nodular echogenicity		p
	Single	Multiple		Non-Hypoechoic	Hypoechoic
N(%)	123	120		204	39
Age(years)	42.41 ± 9.77	43.51 ± 11.13	0.413	42.87 ± 10.57	43.38 ± 9.97	0.778
Men(%)	52(42%)	43(36%)	0.303	78(38.2%)	17(43.6%)	0.288
BMI	23.18 ± 3.05	23.37 ± 3.46	0.656	23.11 ± 3.23	24.12 ± 3.29	0.077
TSH	2.49 ± 1.30	2.36 ± 1.35	0.436	2.43 ± 1.35	2.39 ± 1.22	0.871
FT3	4.55 ± 0.52	4.49 ± 0.47	0.313	4.54 ± 0.50	4.44 ± 0.46	0.269
FT4	16.81 ± 1.71	16.74 ± 2.13	0.755	16.61 ± 1.79	17.63 ± 2.37	0.002
TPOAb-positive	22(17.9%)	18(15%)	0.544	29(14.2%)	11(28.2%)	0.031
TGAb-positive	22(17.9%)	18(15%)	0.544	29(14.2%)	11(28.2%)	0.031
Albumin	45.88 ± 3.06	45.02 ± 2.77	0.022	45.36 ± 2.88	45.97 ± 3.23	0.237
Globulin	29.13 ± 3.92	29.11 ± 3.77	0.97	29.23 ± 3.84	28.54 ± 3.82	0.902
TBIL	9.2(7.2, 11.3)	8.85(6.93, 11.45)	0.504	9.39 ± 3.98	11.53 ± 5.76	0.005
Mental health
sleep quality	6.42 ± 3.67	6.14 ± 2.97	0.512	6.22 ± 3.37	6.64 ± 3.14	0.467
Depression status(%)			0.341			0.001
No depression	54(43.9%)	60(50%)		105(51.5%)	9(23.1%)
Depression	69(56.1%)	60(50%)		99(48.5%)	30(76.9%)
Anxiety status(%)			0.622			0.167
No anxiety	52(42.3%)	47(39.2%)		87(42.6%)	12(30.8%)
Anxiety	71(57.7%)	73(60.8%)		117(57.4%)	27(69.2%)
Stress status(%)			0.680			0.062
No stress	43(35%)	45(37.5%)		79(38.7%)	9(23.1%)
Stress	80(65%)	75(62.5%)		125(61.3%)	30(76.9%)

BMI, body mass index; TSH, thyroid stimulating hormone; FT3, free triiodothyronine; FT4, free thyroxine; TPOAb, thyroid peroxidase antibody; TgAb, thyroglobulin antibody; TBIL, total bilirubin. Bold values indicate p < 0.05.