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. 2023 Dec 16;72(8):1161–1172. doi: 10.2337/db22-0702

Figure 2.

Figure 2

A: Box plot illustrating the mean change in HbA1c (1-year minus baseline) by rs144322333 genotype in the MET only arm. n = 818. B: Stratified analyses by self-reported race/ethnicity. P value was calculated for the subgroup of African American individuals. n = 166. C: Comparison of the influence of rs144322333 genotype on the mean change in HbA1c in all subjects in the MET (n = 818) and PBO (n = 803) arms. The interaction P value is reported. For the purposes of generating the box plots, fractional alleles were converted to “hard calls” by rounding to the nearest integer. AfrAm, African American; AI, American Indian; AsnPI, Asian/Pacific Islander; Hisp, Hispanic/Latino.