Figure 4.
A: Box plot illustrating the mean change in weight (1-year minus baseline) by rs145591055 genotype in the MET only arm. n = 829. B: Box plot stratified by self-reported race/ethnicity. C: Comparison of the influence of rs144322333 genotype on the mean change in weight in all subjects in the MET (n = 829) and PBO (n = 844) arms. The interaction P value is reported. For the purposes of generating the box plots, fractional alleles were converted to “hard calls” by rounding to the nearest integer. AfrAm, African American; AI, American Indian; AsnPI, Asian/Pacific Islander; Hisp, Hispanic/Latino.