Table 5.
Comparison of allergen-induced immunological responses between baseline and at the end of SLIT.
| Parameters | 1 year group | 2 years group | 3 years group |
|---|---|---|---|
| IL-10 | 21.6 ± 12.8 vs 23.7 ± 13.2 | 24.5 ± 13.9 vs 29.8 ± 11.6 | 23.7 ± 11.6 vs 78.9 ± 22.5∗ |
| TGF-beta | 62.3 ± 27.1 vs 75.8 ± 31.4 | 69.4 ± 25.8 vs 87.6 ± 28.5 | 60.6 ± 23.4 vs 124.7 ± 53.5∗ |
| IL-35 | 124 ± 78 vs 119 ± 65 | 133 ± 59 vs 156 ± 71 | 129 ± 63 vs 317 ± 122∗ |
| Treg percentage | 0.4 ± 0.1 vs 0.3 ± 0.2 | 0.5 ± 0.2 vs 0.4 ± 0.1 | 0.38 ± 0.2 vs 2.1 ± 0.6∗ |
| Breg percentage | 0.1 ± 0.02 vs 0.15 ± 0.05 | 0.13 ± 0.03 vs 0.12 ± 0.03 | 0.14 ± 0.05 vs 0.64 ± 0.08∗ |
| Tfr percentage | 0.04 ± 0.01 vs 0.03 ± 0.01 | 0.03 ± 0.02 vs 0.05 ± 0.01 | 0.04 ± 0.02 vs 0.21 ± 0.06 |
All the unit of cytokines were pg/ml; SLIT, sublingual immunotherapy, Treg, regulatory T cell, Breg, regulatory B cell, Tfr, follicular regulatory T cell. ∗ Compared with baseline level, P < 0.05