FIG. 2.

Organization of the M-deficient RV genome. The entire RV genome with its five open reading frames (top), a detailed M cistron region (middle), and the region encompassing a deletion (bottom) are shown. Arrowheads and bars represent transcriptional start and stop signals, respectively. In SAD ΔM, the entire M cistron (SAD L16 nucleotides 2435 to 3176) was removed by a deletion starting within the nontranslated region of the P gene and ending close to the transcriptional stop signal of the M gene.