Table 2.

Prognostic factors for PFS in univariate and multivariate analysis.

	Univariate Analysis HR (%95CI) p-value		Multivariate Analysis HR (%95 CI) p- value
HER2-0 vs HER2 low	1.04 (0.69–1.56)	0.85
Ki67<%20 vs Ki67>%20	1.35 (0.86–2.11)	0.19
Grade 1–2 vs Grade 3	1.80 (1.12–2.88)	0.014	1.49 (0.92–2.41)	0.10
De novo vs recurren disease	0.68 (.46–1.01)	0.057
Visceral met vs non visceral met	3.20 (1.98–5.18)	<0.001	2.70 (1.62–4.52)	<0.001
First-line treatment vs subsequent lines treatment	0.50 (0.33–.74)	0.001	1.76 (1.10–2.82)	0.017
AI vs Fulvestrant	1.70 (1.16–2.51)	0.007	1.47 (0.92–2.33)	0.09

HR:hazard ratio, CI:confidence interval.