Figure 4.

Treatment strategies for cell-based therapies in glaucoma. Cell replacement strategies aim to insert stem cell–derived glial cells and RGCs into their normal anatomic locations, whereas the implantation of glial cells into locations adjacent to RGCs has been shown to promote visual benefit. Furthermore, the injection of cell-derived products such as neurotrophic factors, miRNAs, and extracellular vesicles is a more recently developed modality of neuroprotection.