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. 2023 Jul 11;15(7):1923. doi: 10.3390/pharmaceutics15071923

Table 2.

Machine learning model performances for UKB. The best prediction results, based on the optimal hyperparameter values and the optimal number of PCs, are shown for each model.

Model Hyperparameter a Parameter Value PCs Included Mean Accuracy Std. Dev.
K-Nearest Neighbors K 10 10 91.6% 0.3%
Support Vector Machine Kernel Radial Basis Function 15 94.0% 0.1%
Regularization (C) 10,000
Gamma 10
Random Forest Number of trees 400 16 94.3% 0.1%
Maximum depth of trees 110
Minimum samples for leaf node 2
Minimum samples to split node 3

a Hyperparameter definitions are provided in the Supplementary Methods.