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DNA immunization of woodchucks with plasmids pcDNA3, pWHcIm, and pWHsIm
| Woodchuck | Immunogena | Interval (no. of weeks) | WHV ID50 used for challenge |
|---|---|---|---|
| WH282 | pWHcIm | ||
| WH564 | pWHcIm | ||
| WH880 | None | 105 | |
| WH882 | None | 105 | |
| WH281 | pcDNA3 | 4 | 104 |
| WH574 | pcDNA3 | 4 | 104 |
| WH290 | pWHcIm | 4 | 104 |
| WH291 | pWHcIm | 4 | 104 |
| WH8902 | pWHcIm | 3 | 105 |
| WH8904 | pWHcIm | 3 | 105 |
| WH8899 | pWHsIm | 3 | 105 |
| WH8897 | pWHsIm | 3 | 105 |
WH282 and WH564 were immunized twice with 100 μg of pWHcIm and then three times with 1 mg of pWHcIm but not challenged (see text).
