Figure 2.

Schematic representation of the differential stripping method. (a) Skin is treated with a topical drug formulation; (b) the skin is cleaned and dried; (c) the stratum corneum is removed with 10–15 adhesive tapes, which are taken to drug extraction and analysis; (d) the follicular casts are removed with one or two drops of cyanoacrylate glue and an additional tape, which is taken to drug extraction and analysis; and (e) the remaining skin without the stratum corneum and hair follicles is (f) cut in small fragments and taken to drug analysis. Own authorship. Created with Adobe Illustrator^®, version 27.7.