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Schematic representation of the hair follicle occlusion method. (a) The hair follicles are occluded with enamel or resin, and the skin is then treated with a drug formulation, followed by drug extraction and quantification from the skin layers. (b) The results of drug retention in stratum corneum and remaining skin are compared to those from the non-pretreated skin. Own authorship. Created with Adobe Illustrator®, version 27.7.
