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. 2023 Jul 7;16(7):977. doi: 10.3390/ph16070977

Figure 1.

Figure 1

Blood pressure assessment (a–d), and thrombosis development (e–h). Portal (a), caval (b), and intracranial (superior sagittal sinus) (c) hypertension, and aortal hypotension (d) in mmHg; thrombosis development (eh) in the inferior caval vein (ICV), portal vein (PV), superior sagittal sinus (SSS), and abdominal aorta (AA). Assessment at the end of the sotalol-time period of 15 min, 90 min, and 180 min. Therapy included BPC 157 (10 μg/kg (light gray bars) or 10 ng/kg (dark gray bars)) or saline (5 mL/kg) (white bars). They were given as an intragastric administration at 5 min following sotalol for assessment at 15 min (e), 90 min (f), and 180 min (g) sotalol-time. As a delayed regimen (h), the therapy was given as an intragastric administration at 90 min sotalol-time for assessment at 180 min sotalol-time. Means ± SD, * p ˂ 0.05, at least, vs. control.