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. 2023 Jun 30;11(7):1183. doi: 10.3390/vaccines11071183

Figure 5.

Figure 5

Sex influence on anti-RBD IgA and IgG and anti-spike IgG serum levels at post-vaccination collection periods for BNT162b2, ChAdOx1 nCoV-19, and CoronaVac vaccines. Serum from individuals immunized with ChAdOx1 nCoV-19, BNT162b2, and CoronaVac was collected at the collection times T2 (1 month after application of the second dose: BNT162b2; ChAdOx1 nCoV-19), T3 (4–6 months after application of the second dose or pre-third dose: BNT162b2; ChAdOx1 nCoV-19; CoronaVac), and T4 (1 month after application of the third dose) and evaluated for the influence of sex on antibody production. Detection of anti-RBD IgA (A–C) and IgG (D–F) and anti-spike IgG (G–I) was performed via the enzyme immunoassay (ELISA) described in the methods section. The results are expressed through the index calculated between the ratio: mean optical density (OD) of the sample/cutoff (S/CO-Signal/Cutoff). Each point represents a single individual. The end of the bar indicates the median value and the horizontal bars above and below the median indicate the 95% confidence interval. The Kruskal–Wallis test was used to compare the indices of induced antibodies between vaccines. Statistical significance was adopted for p < 0.05.