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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
A novel attenuated PEDV HSGP strain was generated after co-infection with the HS and SGP-M1 strains. Changes in the nucleotide sequences of the S1 and S2 domains at various co-infection rates, and in three different cell types, are shown.